한국수산과학회

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  • pISSN : 2234-8395
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  • eISSN : 2234-1757

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kfas, vol. 52, no. 2, pp.127-133, April, 2019
DOI. https://doi.org/10.5657/KFAS.2019.0127

Antioxidant and Antihypertension Effects of Enzyme Hydrolysate from
Hippocampus abdominalis
식용 빅벨리 해마(Hippocampus abdominalis) 유래 단백질 가수분해물
의 항산화와 항고혈압 효능

제준건·김현수·이효근·오재영·Lei Wang·노섬1·전유진*
제주대학교 해양생명과학과, 1㈜해천마

Seahorses have long been used as ornamental and medicinal products. The sea horse Hippocampus abdominalis has
a beautiful color and unique shape and is also used for ornamental purposes and as a traditional medicine in China.
This study examined the value of H. abdominalis as a health functional food or food additive. H. abdominalis was
hydrolyzed using seven proteases: flavourzyme, neutrase, alcalase, trypsin, kojizyme, pepsin and protamex. The
yields of all of the enzyme hydrolysates were higher than that of the aqueous extract. Of the enzymatic hydrolysates,
seahorse Protamex hydrolysate (SHP) gave the highest yield and had excellent antioxidant and angiotensin-I converting
enzyme inhibitory activities. It protected Vero cells against oxidative by 2,2-azobis-(2-amidinopropane) dihydrochloride
(AAPH) and antihypertension in Spontaneously Hypertensive Rats. This study attempted to demonstrate H.
abdominalis as a health functional food or food additive in the future.

Keyword : Hippocampus abdominalis, Enzyme hydrolysate, Protamex, Antioxidant, Antihypertension

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